Search results for "perfusion MRI"

Reproducibility of multiphase pseudo-continuous arterial spin labeling and the effect of post-processing analysis methods

2015

Arterial spin labeling (ASL) is an emerging MRI technique for non-invasive measurement of cerebral blood flow (CBF). Compared to invasive perfusion imaging modalities, ASL suffers from low sensitivity due to poor signal-to-noise ratio (SNR), susceptibility to motion artifacts and low spatial resolution, all of which limit its reliability. In this work, the effects of various state of the art image processing techniques for addressing these ASL limitations are investigated. A processing pipeline consisting of motion correction, ASL motion correction imprecision removal, temporal and spatial filtering, partial volume effect correction, and CBF quantification was developed and assessed. To fur…

DCE and DSC perfusion MRI acquisition: diagnostic accuracy during the follow-up of the primary and metastatic intra-axial brain tumors treated by Ste…

Distinguishing radiation necrosis from tumor recurrence and tumor progression is crucial for the evaluation of treatment response and treatment planning. The appearance of treatment-induced tissue necrosis on conventional Magnetic Resonance Imaging (MRI) are very similar to brain tumor recurrence and it could be difficult to differentiate the two entities during the follow-up MRI examinations. Dynamic Susceptibility Contrast-enhanced (DSC) and Dynamic Contrast-Enhanced (DCE) are the MRI perfusion techniques using an exogenous, intravascular, no diffusible gadolinium-based contrast agent. The aim of this study is to compare the diagnostic accuracy of DSC and DCE perfusion MRI in the differen…